Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 4/20 | 0.50 |
| ▸ | HTR3A | P46098 | 3/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.50 |
| ▸ | HTR3B | O95264 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP5 | P51878 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083795 | 0.81 | HTR3A (0.68) | GAAHTR3ACASP1CASP5HRH4 | |
| SCHEMBL17377841 | 0.81 | HTR3E (0.56) | GAAHTR2CHTR3AHTR3EHTR3B | |
| SCHEMBL11201044 | 0.75 | HTR2C (0.70) | HTR2CHTR3ACASP1CASP5HRH4 | |
| SCHEMBL16164244 | 0.72 | HTT (0.68) | GAAHTR2CHTR3AHTR3EHTR3B | |
| SCHEMBL11384876 | 0.72 | CASP1 (0.66) | GAACASP1CASP5HTTSMN1; SMN2 | |
| SCHEMBL11282875 | 0.72 | LMNA (0.58) | GAACASP1CASP5HTTSMN1; SMN2 | |
| SCHEMBL11278102 | 0.72 | LMNA (0.56) | GAACASP1CASP5HTTSMN1; SMN2 | |
| SCHEMBL11201579 | 0.71 | MEN1 (0.50) | GAAHTR1AHTTSMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL7834533 | 0.71 | NSD2 (0.65) | GAAKDM4E | |
| Hydrochloric Acid SCHEMBL7834531 | 0.71 | NSD2 (0.65) | GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |