Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209421 | 0.88 | BCL2 (0.34) | HRH4KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL11200185 | 0.87 | ALDH1A1 (0.39) | HRH4KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL11205447 | 0.85 | HRH4 (0.38) | HRH4KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL11206681 | 0.85 | KDM4E (0.34) | HRH4KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL11199749 | 0.84 | HRH4 (0.36) | HRH4KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL11201723 | 0.83 | KHK (0.39) | HRH4KDM4EALDH1A1 | |
| SCHEMBL11200278 | 0.81 | HRH4 (0.36) | HRH4KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL11205773 | 0.79 | HRH4 (0.36) | HRH4KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL11203278 | 0.78 | KDM4E (0.30) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11201322 | 0.77 | MEN1 (0.43) | KDM4EALDH1A1MAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |