SCHEMBL11201460

SCHEMBL11201460

COc1ccc(NC(=O)c2ccccc2-c2ccccc2)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.56
ALDH1A1 P00352 5/20 0.54
KDM4E B2RXH2 3/20 0.54
MAPT P10636 3/20 0.54
LMNA P02545 3/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
USP2 O75604 1/20 0.54
DUSP3 P51452 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
POLB P06746 2/20 0.53
GAA P10253 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
CASP3 P42574 1/20 0.52
CHRNB2 P17787 2/20 0.49
CHRNB4 P30926 2/20 0.49
CHRNA3 P32297 2/20 0.49
CHRNA4 P43681 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
MMP14 P50281 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507852 0.85 KMT2A (0.65) ALDH1A1KDM4EMAPTLMNAKMT2A
SCHEMBL11193262 0.79 CHRNB2 (0.62) HTTALDH1A1MAPTTDP1CASP3
SCHEMBL34475117 0.77 HTT (0.60) HTTALDH1A1KDM4EMAPTLMNA
SCHEMBL5740948 0.77 LMNA (0.60) HTTALDH1A1KDM4EMAPTLMNA
SCHEMBL5316685 0.76 HTT (0.59) HTTALDH1A1KDM4EMAPTLMNA
SCHEMBL11413881 0.76 CASP3 (0.79) MAPTKMT2AMEN1POLBGAA
SCHEMBL5235657 0.75 HTT (0.58) HTTALDH1A1KDM4EMAPTLMNA
SCHEMBL7337275 0.75 HTT (0.58) HTTALDH1A1KDM4EMAPTLMNA
SCHEMBL14355330 0.74 ALDH1A1 (0.57) HTTALDH1A1KDM4EMAPTLMNA
SCHEMBL14200946 0.74 MAPT (0.43) HTTALDH1A1KDM4EMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4369038-A Transfer-printing paper, its manufacture and uses CIBA-GEIGY LTD. (CH) 1983-01-18 US disclosed