Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201124 | 0.88 | HPGD (0.43) | MAPTHPGDPTGS2ABCB11LMNA | |
| SCHEMBL11204089 | 0.80 | RAB9A (0.43) | MAPTHPGDPTGS2SMN1; SMN2LMNA | |
| SCHEMBL11196344 | 0.78 | HPGD (0.43) | MAPTHPGDPTGS2ABCB11ATM | |
| SCHEMBL7678013 | 0.77 | HPGD (0.45) | MAPTHPGDPTGS2ABCB11SMN1; SMN2 | |
| SCHEMBL11202785 | 0.76 | MAPT (0.39) | MAPTHPGDSMN1; SMN2LMNAATM | |
| SCHEMBL11202156 | 0.75 | AKR1C3 (0.43) | MAPTRAB9ASRD5A2 | |
| SCHEMBL7678233 | 0.73 | MEN1 (0.45) | MAPTHPGDPTGS2SMN1; SMN2LMNA | |
| SCHEMBL8606636 | 0.72 | ALDH1A1 (0.46) | MAPTHPGDPTGS2SMN1; SMN2LMNA | |
| SCHEMBL8604431 | 0.70 | MAPT (0.46) | MAPTHPGDPTGS2ABCB11LMNA | |
| SCHEMBL11198928 | 0.69 | LMNA (0.40) | MAPTHPGDPTGS2ABCB11SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0072013-A1 | Pyrrole compounds as anti-inflammatory and analgesic agents | MERCK & CO. INC. (US) | 1983-02-16 | — | — | EP | claimed |