Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | TXN | P10599 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537553 | 0.73 | CSNK1A1 (0.41) | FBP1BRAFMTORADKNISCH | |
| SCHEMBL1740306 | 0.73 | TXN (0.45) | BRAFTXNTXNRD1MYCMTOR | |
| SCHEMBL2432241 | 0.71 | FBP1 (0.68) | FBP1PDE7APOLBTAAR1 | |
| SCHEMBL5032699 | 0.69 | MTOR (0.45) | TXNTXNRD1MTORADKNISCH | |
| SCHEMBL4923332 | 0.68 | FBP1 (0.46) | FBP1PDE7A | |
| SCHEMBL28588898 | 0.67 | EHMT2 (0.48) | FBP1BRAFGABRA1GABRG2GABRB3 | |
| SCHEMBL6527005 | 0.67 | EHMT2 (0.48) | TXNTXNRD1MTORADKNISCH | |
| SCHEMBL9045818 | 0.67 | MYC (0.43) | TXNTXNRD1MYCGCKFDPS | |
| SCHEMBL857391 | 0.65 | AXL (0.45) | — | |
| SCHEMBL924231 | 0.64 | MTOR (0.36) | BRAFTXNTXNRD1MTORADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402960-A | Antiinflammatory imidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-09-06 | — | — | US | disclosed |