Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201726 | 1.00 | MAPT (0.56) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL11196619 | 0.81 | MMP8 (0.50) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL11196634 | 0.81 | MMP8 (0.50) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL11200962 | 0.79 | S1PR1 (0.44) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11200964 | 0.79 | S1PR1 (0.44) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11193752 | 0.78 | AR (0.64) | MAPTLMNAHTTCYP1A2CYP3A4 | |
| SCHEMBL11193757 | 0.78 | AR (0.64) | MAPTLMNAHTTCYP1A2CYP3A4 | |
| SCHEMBL7578041 | 0.77 | ALDH1A1 (0.60) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL11200354 | 0.77 | IDO1 (0.41) | MAPTLMNAKDM4E | |
| SCHEMBL11198230 | 0.77 | FPR2 (0.46) | MAPTMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4411912-A | Insecticidal isovaleric acid esters | ZOECON CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
| US-4243819-A | Substituted amino acids | ZOECON CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |