Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7576014 | 0.84 | SMN1; SMN2 (0.60) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7584783 | 0.84 | LMNA (0.60) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7584703 | 0.83 | NPC1 (0.53) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7574997 | 0.77 | CA2 (0.44) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7574185 | 0.77 | HPGD (0.57) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL11201726 | 0.77 | MAPT (0.56) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL11201722 | 0.77 | MAPT (0.56) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL9650509 | 0.77 | MEN1 (0.68) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL7582132 | 0.77 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL7584383 | 0.76 | ALOX5 (0.50) | ALDH1A1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |