SCHEMBL6780552

SCHEMBL6780552

O=C(O)C1=CN2CC=Nc3cccc(c32)C1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6667856 0.88 TRPA1 (0.36) TRPA1
Water SCHEMBL10588716 0.72 MAOA (0.34)
SCHEMBL11724902 0.72 SRD5A2 (0.34)
SCHEMBL11202182 0.72 NOTUM (0.39)
SCHEMBL9032480 0.71
Hydrochloric Acid SCHEMBL10432400 0.71 NOTUM (0.38)
Hydrochloric Acid SCHEMBL9223530 0.70
SCHEMBL7210084 0.70
SCHEMBL8775599 0.70 MCL1 (0.40)
SCHEMBL28414326 0.69 NOTUM (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6686356-B2 HERPES VIRUS PHARMACIA & UPJOHN COMPANY 2004-02-03 US disclosed
CN-1099029-A Carbostyril carboxylic acid derivatives, its preparation and purposes TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1995-02-22 CN disclosed
US-5237060-A Cyclization; amination BAYER AKTIENGESELLSCHAFT (DE) 1993-08-17 US disclosed
US-4499270-A INHIBITING THE GROWTH OF MICROORGANISMS RIKER LABORATORIES, INC. (US) 1985-02-12 US disclosed
US-4348521-A BACTERICIDES, FUNGICIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-09-07 US disclosed