SCHEMBL11724902

SCHEMBL11724902

O=C(O)C1=CN2CC=C(O)c3cccc(c32)C1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.34
SRD5A1 P18405 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.30
HSP90AA1 P07900 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10588716 0.72 MAOA (0.34)
SCHEMBL6780552 0.72 TRPA1 (0.35)
SCHEMBL11202182 0.72 NOTUM (0.39)
Hydrochloric Acid SCHEMBL10432400 0.71 NOTUM (0.38)
SCHEMBL7210084 0.70
SCHEMBL8775599 0.70 MCL1 (0.40)
SCHEMBL28414326 0.69 NOTUM (0.31)
SCHEMBL9227676 0.68 GAA (0.33)
SCHEMBL9273390 0.67 MCL1 (0.39)
Hydrochloric Acid SCHEMBL10435581 0.67 GAA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3344262-A1 IMMUNE CELLS HAVING INCREASED IMMUNITY OR RESISTANCE TO AN IMMUNOSUPPRESSIVE CYTOKINE AND USE OF THE SAME Innate Tumor Immunity, Inc. (US) 2018-07-11 EP claimed
WO-2017040670-A1 IMMUNE CELLS HAVING INCREASED IMMUNITY OR RESISTANCE TO AN IMMUNOSUPPRESSIVE CYTOKINE AND USE OF THE SAME IFM THERAPEUTICS, INC (US) 2017-03-09 WO claimed
US-20170056448-A1 IMMUNE CELLS HAVING INCREASED IMMUNITY OR RESISTANCE TO AN IMMUNOSUPPRESSIVE CYTOKINE AND USE OF THE SAME IFM THERAPEUTICS, INC (US) 2017-03-02 US claimed
WO-2023091503-A1 NUCLEIC ACID COMPOSITIONS AND USES THEREOF SURGE Therapeutics, Inc. (US) 2023-05-25 WO disclosed
EP-3922279-A1 DRUG DELIVERY COMPOSITIONS AND USES THEREOF Dana Farber Cancer Institute, Inc. (US) 2021-12-15 EP disclosed
US-20210246211-A1 DRUG DELIVERY COMPOSITIONS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2021-08-12 US disclosed
US-11021539-B2 Drug delivery compositions and uses thereof DANA-FARBER CANCER INSTITUTE, INC. (US) 2021-06-01 US disclosed
EP-3506884-B1 DRUG DELIVERY COMPOSITIONS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-05-05 EP disclosed
US-20210059953-A1 LIPID NANOPARTICLE FORMULATIONS OF NON-VIRAL, CAPSID-FREE DNA VECTORS GENERATION BIO CO. 2021-03-04 US disclosed
EP-3768236-A1 COMPOSITIONS AND METHODS FOR CANCER TREATMENT Dana-Farber Cancer Institute, Inc. (US) 2021-01-27 EP disclosed
US-20210008048-A1 COMPOSITIONS AND METHODS FOR CANCER TREATMENT DANA-FARBER CANCER INSTITUTE, INC. (US) 2021-01-14 US disclosed
US-20190083626-A1 DRUG DELIVERY COMPOSITIONS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2019-03-21 US disclosed
WO-2019051289-A1 LIPID NANOPARTICLE FORMULATIONS OF NON-VIRAL, CAPSID-FREE DNA VECTORS GENERATION BIO CO. (US) 2019-03-14 WO disclosed
EP-3344262-A1 IMMUNE CELLS HAVING INCREASED IMMUNITY OR RESISTANCE TO AN IMMUNOSUPPRESSIVE CYTOKINE AND USE OF THE SAME Innate Tumor Immunity, Inc. (US) 2018-07-11 EP disclosed
WO-2018045058-A1 DRUG DELIVERY COMPOSITIONS AND USES THEREOF DANA-FARBER CANCER INSTITUTE, INC. (US) 2018-03-08 WO disclosed
WO-2017040670-A1 IMMUNE CELLS HAVING INCREASED IMMUNITY OR RESISTANCE TO AN IMMUNOSUPPRESSIVE CYTOKINE AND USE OF THE SAME IFM THERAPEUTICS, INC (US) 2017-03-09 WO disclosed
US-20170056448-A1 IMMUNE CELLS HAVING INCREASED IMMUNITY OR RESISTANCE TO AN IMMUNOSUPPRESSIVE CYTOKINE AND USE OF THE SAME IFM THERAPEUTICS, INC (US) 2017-03-02 US disclosed
US-4051247-A ANTIBACTERIAL AGENTS RIKER LABORATORIES, INC. (US) 1977-09-27 US disclosed
US-3985753-A ANTIBACTERIAL AGENTS RIKER LABORATORIES, INC. (US) 1976-10-12 US disclosed
US-3976651-A BACTERICIDE RIKER LABORATORIES, INC. (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210008048-A1 COMPOSITIONS AND METHODS FOR CANCER TREATMENT STING1, IL15, MAPK15 SRD5A2 3822/4885SRD5A1 2672/4885CTDSP1 2331/4885
US-20190083626-A1 DRUG DELIVERY COMPOSITIONS AND USES THEREOF STING1, IL15, IL15RA SRD5A2 2405/4885SRD5A1 1296/4885CTDSP1 2579/4885
US-20210059953-A1 LIPID NANOPARTICLE FORMULATIONS OF NON-VIRAL, CAPSID-FREE DNA VECTORS HDLBP, POLN, NPC1 SRD5A2 4806/4885SRD5A1 4765/4885CTDSP1 115/4885
US-20170056448-A1 IMMUNE CELLS HAVING INCREASED IMMUNITY OR RESISTANCE TO AN IMMUNOSUPPRESSIVE CYTOKINE AND USE OF THE SAME IL2, IFNG, IL2RA SRD5A2 2581/4885SRD5A1 2725/4885CTDSP1 4642/4885
US-20210246211-A1 DRUG DELIVERY COMPOSITIONS AND USES THEREOF STING1, IL15, IL15RA SRD5A2 2405/4885SRD5A1 1296/4885CTDSP1 2579/4885
US-11021539-B2 Drug delivery compositions and uses thereof STING1, IL15, IL15RA SRD5A2 2405/4885SRD5A1 1296/4885CTDSP1 2579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.