Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 2/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | PYGM | P11217 | 2/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920209 | 0.96 | CACNA1F (0.45) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL10786897 | 0.92 | ADORA3 (0.52) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL9691613 | 0.88 | ADORA3 (0.49) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL10923715 | 0.87 | CACNA1F (0.44) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL11363163 | 0.86 | GAA (0.48) | KDM4EALDH1A1KMT2AHSD17B10SMN1; SMN2 | |
| SCHEMBL9689715 | 0.85 | ADORA3 (0.49) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL9689619 | 0.83 | ADORA3 (0.47) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL10643307 | 0.82 | MEN1 (0.61) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 | |
| SCHEMBL11372181 | 0.82 | KDM4E (0.57) | CACNA1CADORA3KDM4EALDH1A1KMT2A | |
| SCHEMBL11366080 | 0.81 | CACNA1C (0.38) | CACNA1CCACNA1FCACNA1DCACNA1SADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088938-A1 | Use of pyridine compounds for the manufacture of medicaments with an antihypoxemia and ischemia-protective activity | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |