Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252080 | 0.86 | RXRA (0.49) | RXRARXRBRXRGCFDF11 | |
| SCHEMBL10145754 | 0.86 | RXRA (0.49) | RXRARXRBRXRGCFDF11 | |
| SCHEMBL11207038 | 0.84 | ADRB2 (0.45) | DHODHFNTAFNTBCYP3A4CYP2C9 | |
| SCHEMBL7815678 | 0.81 | PTPN5 (0.55) | RXRARXRBRXRGDHODHPTPN5 | |
| SCHEMBL5888495 | 0.79 | KIF11 (0.49) | RXRARXRBRXRGIRAK4PSEN1 | |
| SCHEMBL5216031 | 0.79 | KIF11 (0.49) | RXRARXRBRXRGIRAK4PSEN1 | |
| SCHEMBL30913871 | 0.79 | ADRB2 (0.52) | — | |
| SCHEMBL10801845 | 0.79 | ADRB2 (0.52) | — | |
| SCHEMBL3721175 | 0.79 | PTPN5 (0.51) | DHODHPTPN5PSEN1PSEN2APH1B | |
| SCHEMBL17795032 | 0.78 | RXRA (0.42) | RXRARXRBRXRGDHODHPTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0092194-A1 | Method of obtaining optically active half esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-26 | — | — | EP | disclosed |