Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592353 | 0.75 | CASP6 (0.57) | POLBCYP1A2SMN1; SMN2HSD17B1HSD17B2 | |
| SCHEMBL1044088 | 0.74 | CYP1A2 (0.62) | POLBCYP1A2CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL28065895 | 0.73 | PLAU (0.50) | CYP1A2HSD17B1HSD17B2GRIN2DGRIN2A | |
| SCHEMBL9815043 | 0.72 | CYP1A2 (0.57) | POLBCYP1A2CYP2C19SMN1; SMN2CYP2C9 | |
| SCHEMBL8109469 | 0.71 | TIMP3 (0.47) | TDP1CYP1A2CYP2C19CA12CA1 | |
| SCHEMBL8115834 | 0.70 | NT5E (0.67) | POLBCYP1A2CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL9850232 | 0.70 | TDP1 (0.61) | POLBTDP1CYP2C19SMN1; SMN2KDM4E | |
| SCHEMBL890383 | 0.69 | CYP1A2 (0.70) | POLBCYP1A2CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL12412510 | 0.68 | CYP1A2 (0.56) | POLBCYP1A2CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL8109860 | 0.68 | APEX1 (0.61) | POLBTDP1CYP1A2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090114-A2 | Reactive dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-10-05 | — | — | EP | disclosed |