Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671022 | 0.83 | KDM4E (0.61) | CYP1A2KMT2APOLBCA1CA2 | |
| SCHEMBL8784533 | 0.79 | CASP6 (0.59) | CYP1A2KMT2APOLBHSD17B1HSD17B2 | |
| SCHEMBL6240037 | 0.78 | FGF1 (0.48) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL13990189 | 0.77 | CYP1A2 (1.00) | CYP1A2NPSR1KMT2APOLBCYP2C19 | |
| SCHEMBL8115834 | 0.77 | NT5E (0.67) | CYP1A2KMT2APOLBCA12CA1 | |
| SCHEMBL10621974 | 0.76 | TGM2 (0.49) | CASP6 | |
| SCHEMBL12412510 | 0.75 | CYP1A2 (0.56) | CYP1A2NPSR1KMT2APOLBCYP3A4 | |
| SCHEMBL7223229 | 0.75 | CASP6 (0.55) | CYP1A2KMT2APOLBCA12CA1 | |
| SCHEMBL9219483 | 0.75 | TNNI3 (0.65) | KMT2APOLBHTR6CYP3A4MEN1 | |
| SCHEMBL11204164 | 0.74 | POLB (0.45) | CYP1A2POLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8182790-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-05-22 | — | — | US | disclosed |
| EP-1814598-B1 | CONTRAST AGENTS TO TARGET EXTRACELLULAR MATRIX | GE HEALTHCARE AS (NO) | 2011-01-12 | — | — | EP | disclosed |
| EP-2243496-A2 | Contrast agents to target extracellular matrix | GE HEALTHCARE AS (NO) | 2010-10-27 | — | — | EP | disclosed |
| US-20090208412-A1 | Contrast Agents | GE HEALTHCARE AS (NO) | 2009-08-20 | — | — | US | disclosed |
| EP-1814598-A2 | CONTRAST AGENTS TO TARGET EXTRACELLULAR MATRIX | GE Healthcare AS (NO) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006054904-A2 | CONTRAST AGENTS TO TARGET EXTRACELLULAR MATRIX | GE HEALTHCARE AS (NO) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208412-A1 | Contrast Agents | COL2A1, COL1A1, COL14A1 | CYP1A2 1635/4885NPSR1 2387/4885KMT2A 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.