Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.32 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209928 | 0.92 | ALDH1A1 (0.42) | KMT2AALDH1A1MEN1MAPTGRM5 | |
| SCHEMBL11206464 | 0.92 | BRD4 (0.38) | KMT2AALDH1A1MEN1MAPTGRM5 | |
| SCHEMBL11216136 | 0.84 | ALDH1A1 (0.54) | KMT2AALDH1A1MEN1MAPTGRM5 | |
| SCHEMBL11210954 | 0.83 | KMT2A (0.40) | KMT2AALDH1A1MEN1MAPTHPGD | |
| SCHEMBL11204757 | 0.81 | KMT2A (0.44) | KMT2AALDH1A1MEN1MAPTGRM5 | |
| SCHEMBL10746247 | 0.79 | KMT2A (0.35) | KMT2AALDH1A1MEN1MAPTGRM5 | |
| SCHEMBL11558311 | 0.78 | HAO1 (0.36) | EGFRHAO1FNTAFNTBPGGT1B | |
| SCHEMBL11201186 | 0.77 | BRD4 (0.56) | KMT2AALDH1A1MEN1MAPTGRM5 | |
| SCHEMBL22580621 | 0.76 | ALDH1A1 (0.54) | KMT2AALDH1A1MEN1MAPTGRM5 | |
| SCHEMBL11200196 | 0.76 | CA2 (0.47) | KMT2AALDH1A1MEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4417039-A | Cis-enyne aromatic and aromatic heterocyclic polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-11-22 | — | — | US | disclosed |
| US-4380619-A | POLYBENZOTHIAZOLES; N-HETEROCYCLIC POLYMERS; SOLUBILITY; HEAT RESISTANCE; AIRCRAFT; AEROSPACE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-04-19 | — | — | US | disclosed |