Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22580621 | 0.92 | ALDH1A1 (0.54) | ALDH1A1KMT2AHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11218804 | 0.92 | HPGD (0.49) | ALDH1A1KMT2AHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11213207 | 0.92 | ALDH1A1 (0.58) | ALDH1A1KMT2AHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11204754 | 0.84 | KMT2A (0.38) | ALDH1A1KMT2AHPGDSMN1; SMN2LMNA | |
| SCHEMBL11204757 | 0.82 | KMT2A (0.44) | ALDH1A1KMT2AHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11211251 | 0.81 | HPGD (0.59) | ALDH1A1KMT2AHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL11201186 | 0.81 | BRD4 (0.56) | ALDH1A1KMT2AMEN1MAPTTDP1 | |
| SCHEMBL10352333 | 0.78 | NR1H3 (0.53) | ALDH1A1KMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL3447118 | 0.76 | HSPA1A (0.41) | ALDH1A1KDM4EHSPA1APABPC1TYMS | |
| SCHEMBL11206464 | 0.76 | BRD4 (0.38) | ALDH1A1KMT2AHPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4417039-A | Cis-enyne aromatic and aromatic heterocyclic polymers | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 1983-11-22 | — | — | US | disclosed |