Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11201833 | 0.89 | RAB9A (0.45) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11204144 | 0.85 | RAB9A (0.43) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11210924 | 0.82 | NPC1 (0.44) | NPC1MEN1KMT2AMAPTGAA | |
| SCHEMBL16838610 | 0.79 | MAPT (0.50) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL11210434 | 0.77 | UTS2R (0.45) | RAB9AKDM4EGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11481793 | 0.77 | KDM4E (0.51) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL14440013 | 0.74 | CXCL8 (0.43) | KDM4EMAPTALDH1A1CYP1A2 | |
| SCHEMBL11201712 | 0.72 | CASR (0.42) | RAB9ANPC1MEN1KMT2AKDM4E | |
| SCHEMBL14440012 | 0.72 | LMNA (0.43) | MEN1KMT2AMAPTGAAPOLB | |
| SCHEMBL23715809 | 0.72 | NPC1 (0.50) | RAB9ANPC1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006713-B1 | NOVEL ALPHA-AMINO-PHENYLACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION, THEIR USE AS HERBICIDAL, ALGICIDAL AND PLANT GROWTH REGULATING AGENTS, AND HERBICIDAL, ALGICIDAL AND PLANT GROWTH REGULATING COMPOSITIONS CONTAINING THEM | JANSSEN PHARMACEUTICA N.V. (BE) | 1983-07-13 | — | — | EP | disclosed |
| US-4246429-A | HERBICIDES, ALGICIDES, PLANT GROWTH REGULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 1981-01-20 | — | — | US | disclosed |
| EP-0006713-A1 | Novel alpha-amino-phenylacetic acid derivatives, processes for their preparation, their use as herbicidal, algicidal and plant growth regulating agents, and herbicidal, algicidal and plant growth regulating compositions containing them | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-01-09 | — | — | EP | disclosed |