Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459934 | 0.87 | CA12 (0.44) | APPHSD17B1HSD17B2GSTP1EGFR | |
| SCHEMBL5622659 | 0.84 | ACHE (0.45) | HSD17B1HSD17B2EGFRMAOBNPC1 | |
| SCHEMBL3262111 | 0.82 | ESR2 (0.52) | APPABL1ABCB1BCRNPC1 | |
| SCHEMBL10918406 | 0.82 | CYP11B1 (0.44) | ABL1ABCB1BCRNPC1RAB9A | |
| SCHEMBL6841236 | 0.82 | MEN1 (0.38) | NPC1RAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL4468568 | 0.82 | MEN1 (0.40) | HSD17B1HSD17B2MAOBTP53MAPK1 | |
| SCHEMBL8327622 | 0.82 | MAOB (0.43) | APPMAPK14MAOBNPC1TP53 | |
| SCHEMBL7033071 | 0.81 | CA4 (0.43) | ABCB1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL15066961 | 0.80 | ALDH1A1 (0.41) | HSD17B1HSD17B2SMN1; SMN2CA12CA1 | |
| SCHEMBL8529256 | 0.79 | CYP1A1 (0.45) | HSD17B1HSD17B2ABL1ABCB1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089137-A1 | Substituted pyridazines, their use as plant growth regulators, and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1983-09-21 | — | — | EP | disclosed |