Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 5/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.52 |
| ▸ | BCR | P11274 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459934 | 0.87 | CA12 (0.44) | ESR2ABL1ABCB1BCRTP53 | |
| SCHEMBL5622659 | 0.84 | ACHE (0.45) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL28453013 | 0.82 | ABL1 (0.38) | ESR2ABL1ABCB1BCRAPP | |
| SCHEMBL8327622 | 0.82 | MAOB (0.43) | TP53KDM4EMEN1MAPTKMT2A | |
| SCHEMBL11205461 | 0.82 | APP (0.39) | ABL1ABCB1BCRTP53APP | |
| SCHEMBL6841236 | 0.82 | MEN1 (0.38) | KDM4EMEN1MAPTKMT2ACYP3A4 | |
| SCHEMBL4468568 | 0.82 | MEN1 (0.40) | TP53KDM4EMEN1MAPTKMT2A | |
| SCHEMBL10918406 | 0.82 | CYP11B1 (0.44) | ABL1ABCB1BCRKDM4EMEN1 | |
| SCHEMBL7033071 | 0.81 | CA4 (0.43) | ABCB1TP53KDM4EMEN1MAPT | |
| SCHEMBL4288060 | 0.81 | HSD17B1 (0.44) | ESR2ABL1ABCB1BCRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813542-A1 | AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-12-29 | — | — | EP | claimed |
| WO-1996009823-A9 | HYPOGLYCEMIC AGENT FROM CRYPTOLEPIS | — | 1996-05-23 | — | — | WO | claimed |
| US-7648811-B2 | Branched polyarylene ethers and processes for the preparation thereof | XEROX CORPORATION (US) | 2010-01-19 | — | — | US | disclosed |
| US-7396895-B2 | Branched polyarylene ethers and processes for the preparation thereof | XEROX CORPORATION (US) | 2008-07-08 | — | — | US | disclosed |
| US-20080118853-A1 | BRANCHED POLYARYLENE ETHERS AND PROCESSES FOR THE PREPARATION THEREOF | XEROX CORPORATION (US) | 2008-05-22 | — | — | US | disclosed |
| US-7067608-B2 | Process for preparing branched polyarylene ethers | XEROX CORPORATION (US) | 2006-06-27 | — | — | US | disclosed |
| US-20050208416-A1 | Branched polyarylene ethers and processes for the preparation thereof | XEROX CORPORATION | 2005-09-22 | — | — | US | disclosed |
| US-20050154178-A1 | Process for preparing branched polyarylene ethers | XEROX CORPORATION | 2005-07-14 | — | — | US | disclosed |
| WO-2001091796-A2 | METHODS, COMPOUNDS AND COMPOSITIONS FOR TREATING GOUT | GUILFORD PHARMACEUTICALS INC. (US) | 2001-12-06 | — | — | WO | disclosed |
| WO-1996009823-A9 | HYPOGLYCEMIC AGENT FROM CRYPTOLEPIS | — | 1996-05-23 | — | — | WO | disclosed |