Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918406 | 0.96 | CYP11B1 (0.44) | CA4CYP1A2CYP2A6TNKSCYP19A1 | |
| SCHEMBL8531326 | 0.88 | LTA4H (0.53) | CA4CYP1A2CYP2A6KDM4EMEN1 | |
| SCHEMBL323109 | 0.87 | DYRK1A (0.49) | CYP1A2CYP2A6NPC1RAB9AKDM4E | |
| SCHEMBL459934 | 0.86 | CA12 (0.44) | CYP1A2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL15066961 | 0.83 | ALDH1A1 (0.41) | CA4CYP1A2CYP2A6KDM4EMEN1 | |
| SCHEMBL5622659 | 0.83 | ACHE (0.45) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL8529256 | 0.82 | CYP1A1 (0.45) | CYP1A2CYP2A6NPC1RAB9AABCB1 | |
| SCHEMBL7462944 | 0.82 | ABL1 (0.50) | CA4NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8089523 | 0.82 | CYP1A2 (0.53) | CYP1A2CYP2A6CYP19A1NPC1RAB9A | |
| SCHEMBL16719334 | 0.82 | NFE2L2 (0.46) | CYP1A2CYP2A6NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424180-A | Photochromic fused naphthopyran systems with special substituents for obtaining high lightening speeds | 罗登斯托克有限责任公司 | 2021-02-26 | — | — | CN | claimed |
| US-6180835-B1 | RETRO-ETHYNYLATION PROCESS OF A CYCLOPROPYLPROPYNOL COMPOUND; PREPARING AN INTERMEDIATE IN SYNTHESIS OF DRUG HAVING ANTI-HIV ACTIVITY | KURARAY CO., LTD. (JP) | 2001-01-30 | — | — | US | claimed |
| US-4650868-A | 7-deazapurine derivatives useful as antitumor agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-03-17 | — | — | US | claimed |
| EP-0072346-B1 | AMIDINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOUNDS CONTAINING THEM AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-04-09 | — | — | EP | claimed |
| US-4397783-A | HYDRODEHALOGENATION WITH AN ORGANOTIN HYDRIDE | PFIZER INC. (US) | 1983-08-09 | — | — | US | claimed |
| EP-0005586-B1 | 2,4,6-TRIS-(SUBSTITUTED-AMINO)-S-TRIAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1982-04-28 | — | — | EP | claimed |
| CN-107954999-B | Oxadiazole ring-containing compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-107935803-A | A kind of synthetic method of 1,2 cyclohexadione compounds | 浙江工业大学 | 2018-04-20 | — | — | CN | disclosed |
| EP-3068758-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | The Wistar Institute Of Anatomy And Biology (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015082592-A2 | METHOD FOR PREPARING AMINOARYLBORANE COMPOUNDS OR DERIVATIVES THEREOF | Universite de Bordeaux (FR) | 2015-06-11 | — | — | WO | disclosed |
| EP-2881398-A1 | Method for preparing aminoarylborane compounds or derivatives thereof | Université de Bordeaux I (FR) | 2015-06-10 | — | — | EP | disclosed |
| WO-2015073864-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | THE WISAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2015-05-21 | — | — | WO | disclosed |
| CN-1231816-C | Photoresist compositions | SUMITOMO CHEMICAL CO (JP) | 2005-12-14 | — | — | CN | disclosed |
| US-4684747-A | ANTITUMOR, ALKYLATING AGENTS | YALE UNIVERSITY (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0223739-A1 | Dibenzoxaphosphorine | CIBA-GEIGY AG (CH) | 1987-05-27 | — | — | EP | disclosed |
| EP-0181289-A2 | Process for stabilizing a photographic material containing a magenta coupler | CIBA-GEIGY AG (CH) | 1986-05-14 | — | — | EP | disclosed |
| EP-0005586-B1 | 2,4,6-TRIS-(SUBSTITUTED-AMINO)-S-TRIAZINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AMERICAN CYANAMID COMPANY (US) | 1982-04-28 | — | — | EP | disclosed |
| US-4251655-A | GASTRIC ACID ANTISECRETORY AGENTS | MCNEILAB, INC. (US) | 1981-02-17 | — | — | US | disclosed |
| EP-0005586-A1 | 2,4,6-Tris-(substituted-amino)-S-triazines, process for their preparation and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-11-28 | — | — | EP | disclosed |
| US-4110460-A | ANTIINFLAMMATORY, ANALGESIC | METABIO (FR) | 1978-08-29 | — | — | US | disclosed |