SCHEMBL11205508

SCHEMBL11205508

Oc1cc(O)cc(Oc2nnn[nH]2)c1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.35
HSP90AA1 P07900 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5106372 0.88 PTPN1 (0.42)
Bromide SCHEMBL4792607 0.82 PTPN1 (0.38)
SCHEMBL11209033 0.72 MAOB (0.43)
SCHEMBL14112763 0.69 ALDH1A1 (0.48)
SCHEMBL9505524 0.69 ALDH1A1 (0.45)
SCHEMBL5032127 0.68 HSP90AA1 (0.58) BACE1HSP90AA1
SCHEMBL8864399 0.63 BACE1 (0.43) BACE1HSP90AA1
SCHEMBL31031424 0.58 BACE1 (0.79) BACE1HSP90AA1
SCHEMBL5890304 0.58 MEN1 (0.74) HSP90AA1
SCHEMBL9777392 0.57 BACE1 (0.38) BACE1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0034925-B1 5-(DIHYDROXYPHENOXY) TETRAZOLES AS SWEETENERS ELI LILLY AND COMPANY (US) 1983-05-04 EP claimed
EP-0034925-A1 5-(Dihydroxyphenoxy) tetrazoles as sweeteners ELI LILLY AND COMPANY (US) 1981-09-02 EP claimed
EP-0034925-B1 5-(DIHYDROXYPHENOXY) TETRAZOLES AS SWEETENERS ELI LILLY AND COMPANY (US) 1983-05-04 EP disclosed
US-4356207-A Sweetening with 5-(dihydroxyphenoxy) tetrazoles ELI LILLY AND COMPANY (US) 1982-10-26 US disclosed
US-4309446-A 5-(Dihydroxyphenoxy)tetrazoles and use as sweeteners for medical compositions ELI LILLY AND COMPANY (US) 1982-01-05 US disclosed
EP-0034925-A1 5-(Dihydroxyphenoxy) tetrazoles as sweeteners ELI LILLY AND COMPANY (US) 1981-09-02 EP disclosed