Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11211500 | 0.87 | KMT2A (0.34) | MAOBGAAKMT2AMAPTALOX12 | |
| SCHEMBL11204093 | 0.79 | CA2 (0.39) | GAAKMT2AMAPTALOX12LMNA | |
| SCHEMBL11204056 | 0.78 | KDM4E (0.34) | KMT2AMAPTALOX12MEN1LMNA | |
| SCHEMBL11203013 | 0.75 | ALDH1A1 (0.41) | MAPTALOX12LMNATP53TSHR | |
| SCHEMBL11205508 | 0.72 | BACE1 (0.35) | — | |
| SCHEMBL11204100 | 0.70 | CA1 (0.30) | LMNAHSD17B10MMP9 | |
| SCHEMBL2711865 | 0.66 | MEN1 (0.56) | MAOBF2KMT2AMEN1CAMK2A | |
| SCHEMBL2714037 | 0.65 | MAOB (0.54) | MAOBF2GAAKMT2AMAPT | |
| SCHEMBL14112763 | 0.65 | ALDH1A1 (0.48) | MAOBGAAKMT2AMAPTMEN1 | |
| SCHEMBL14556361 | 0.64 | NOX1 (0.40) | ALOX12KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034925-B1 | 5-(DIHYDROXYPHENOXY) TETRAZOLES AS SWEETENERS | ELI LILLY AND COMPANY (US) | 1983-05-04 | — | — | EP | disclosed |
| US-4356207-A | Sweetening with 5-(dihydroxyphenoxy) tetrazoles | ELI LILLY AND COMPANY (US) | 1982-10-26 | — | — | US | disclosed |
| US-4309446-A | 5-(Dihydroxyphenoxy)tetrazoles and use as sweeteners for medical compositions | ELI LILLY AND COMPANY (US) | 1982-01-05 | — | — | US | disclosed |
| EP-0034925-A1 | 5-(Dihydroxyphenoxy) tetrazoles as sweeteners | ELI LILLY AND COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |