SCHEMBL9505524

SCHEMBL9505524

COc1ccc(Oc2nnn[nH]2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
RAB9A P51151 5/20 0.42
NPC1 O15118 4/20 0.42
LTA4H P09960 2/20 0.42
HAO1 Q9UJM8 2/20 0.41
XDH P47989 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
SCN4A P35499 1/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14112763 0.81 ALDH1A1 (0.48) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL14076384 0.80 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ACA1CA2
SCHEMBL587838 0.74
SCHEMBL672108 0.73 KDM4E (0.50) ALDH1A1KMT2ACA12CA1CA2
SCHEMBL11204902 0.73 SMN1; SMN2 (0.39) ALDH1A1CA12CA1CA2CA7
SCHEMBL18758173 0.72 XDH (0.50) ALDH1A1KMT2ACA12CA1CA2
SCHEMBL11205508 0.69 BACE1 (0.35)
SCHEMBL6150323 0.69 LTA4H (0.47) ALDH1A1LTA4HSMN1; SMN2NPSR1MAPT
SCHEMBL11580995 0.68 CA1 (0.79) ALDH1A1MEN1KMT2ACA12CA1
SCHEMBL83811 0.68 CA1 (0.79) ALDH1A1MEN1KMT2ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0325336-B1 OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PESTICIDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-08-04 EP disclosed
US-4929628-A Oxadiazole compounds, their preparation and their use as pesticides SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B. V. (NL) 1990-05-29 US disclosed
EP-0325336-A1 Oxadiazole compounds, their preparation and their use as pesticides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-07-26 EP disclosed