Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4792607 | 0.93 | PTPN1 (0.38) | PTPN1POLBCYP2C9ALDH1A1 | |
| SCHEMBL11205508 | 0.88 | BACE1 (0.35) | — | |
| Diorcinol SCHEMBL29629136 | 0.74 | ALDH1A1 (0.60) | PTPN1POLBALDH1A1CYP3A4HCAR1 | |
| Diorcinol SCHEMBL28744720 | 0.74 | ALDH1A1 (0.60) | PTPN1POLBALDH1A1CYP3A4HCAR1 | |
| SCHEMBL11204242 | 0.74 | ALDH1A1 (0.42) | CYP2C9ALDH1A1ALPLCYP3A4CYP2C19 | |
| SCHEMBL9505524 | 0.67 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL11209033 | 0.66 | MAOB (0.43) | — | |
| SCHEMBL29215231 | 0.65 | LTA4H (0.54) | PTPN1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL296714 | 0.64 | PTPN1 (0.67) | PTPN1POLBALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL31507600 | 0.64 | PTPN1 (0.67) | PTPN1POLBALDH1A1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293775-A1 | Substituted Diphenylethers, -Amines, -Sulfides and -Methanes for the Treatment of Respiratory Disease | ASTRAZENECA AB (SE) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293775-A1 | Substituted Diphenylethers, -Amines, -Sulfides and -Methanes for the Treatment of Respiratory Disease | PNMT, SQOR, SMS | PTPN1 4039/4885POLB 2371/4885CYP2C9 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.