Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214432 | 0.88 | CXCR4 (0.42) | CXCR4ALDH1A1SMN1; SMN2BCHEHTT | |
| SCHEMBL11211821 | 0.85 | KDM4E (0.40) | CXCR4CYP2D6ALDH1A1SMN1; SMN2BCHE | |
| SCHEMBL11207623 | 0.85 | CXCR4 (0.41) | CXCR4ALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL7525610 | 0.76 | LMNA (0.35) | LMNACYP1A2CYP2D6SCN1ASCN2A | |
| SCHEMBL20758863 | 0.73 | EPHX1 (0.41) | CXCR4CYP2D6ALDH1A1SMN1; SMN2BCHE | |
| SCHEMBL11151811 | 0.73 | KDM4E (0.43) | LMNAHTTKDM4EMMP1 | |
| SCHEMBL12514126 | 0.71 | CXCR4 (0.49) | CXCR4LMNAALDH1A1KDM4E | |
| SCHEMBL11237882 | 0.70 | KDM4E (0.39) | LMNAALDH1A1BCHEHTTKDM4E | |
| SCHEMBL11453276 | 0.70 | KDM4E (0.47) | CXCR4LMNAALDH1A1SMN1; SMN2HTT | |
| SCHEMBL26529447 | 0.69 | EPHX1 (0.41) | LMNACYP1A2CYP2D6SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0018948-B1 | N-SUBSTITUTED DERIVATIVES OF ASPARTIC ACID, PROCESS FOR THEIR PREPARATION, THEIR USE AND EPOXY RESINS PRODUCED WITH THEIR AID | CIBA-GEIGY AG (CH) | 1983-07-13 | — | — | EP | claimed |
| US-4284755-A | REACTING A MALEIC MONOESTER AND A DIAMINE | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | claimed |
| US-4284755-A | REACTING A MALEIC MONOESTER AND A DIAMINE | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |