Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380230 | 0.85 | EPHX2 (0.39) | LMNASMN1; SMN2CYP2D6ALDH1A1CYP3A4 | |
| SCHEMBL7412459 | 0.81 | THRB (0.41) | LMNACYP2D6ALDH1A1TSHRMAPT | |
| SCHEMBL7377849 | 0.81 | THRB (0.41) | LMNACYP2D6ALDH1A1TSHRMAPT | |
| SCHEMBL7379026 | 0.78 | THRB (0.44) | LMNASMN1; SMN2CYP2D6ALDH1A1TSHR | |
| SCHEMBL26529447 | 0.78 | EPHX1 (0.41) | LMNAMMP1MMP2SMN1; SMN2CYP2D6 | |
| SCHEMBL38058 | 0.77 | EPHX1 (0.40) | LMNACYP2D6EPHX1 | |
| SCHEMBL38057 | 0.77 | EPHX1 (0.40) | LMNACYP2D6EPHX1 | |
| SCHEMBL10825239 | 0.76 | EPHX1 (0.43) | LMNASMN1; SMN2CYP2D6HPGDEPHX1 | |
| SCHEMBL19744864 | 0.76 | EPHX1 (0.43) | LMNASMN1; SMN2CYP2D6HPGDEPHX1 | |
| SCHEMBL11205755 | 0.76 | CXCR4 (0.39) | LMNAMMP1SMN1; SMN2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922054-B1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET (HU) | 2002-08-14 | — | — | EP | disclosed |
| US-6235707-B1 | Anticoagulant peptidyl-arginine aldehyde derivatives | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2001-05-22 | — | — | US | disclosed |
| EP-0922054-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | GYOGYSZERKUTATO INTEZET KFT. (HU) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997046576-A1 | ANTICOAGULANT PEPTIDYL-ARGININE ALDEHYDE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1997-12-11 | — | — | WO | disclosed |