Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 10/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676895 | 0.81 | RAB9A (0.48) | RECQLALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11531019 | 0.78 | ALDH1A1 (0.44) | RECQLALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL687742 | 0.77 | ALDH1A1 (0.49) | RECQLALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11531240 | 0.76 | TSHR (0.53) | RECQLALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL29020269 | 0.76 | ALDH1A1 (0.60) | RECQLALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11158867 | 0.76 | MEN1 (0.47) | RECQLALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11207102 | 0.73 | NPC1 (0.43) | NPSR1ALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL28030373 | 0.72 | CYP3A4 (0.56) | NPSR1ALDH1A1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL867896 | 0.71 | ALDH1A1 (0.53) | RECQLALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL14828743 | 0.71 | ALDH1A1 (0.53) | RECQLALDH1A1CYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023938-B1 | PREPARATION OF PYRROLE-2-ACETATES | McNeilab, Inc. (US) | 1983-07-20 | — | — | EP | claimed |