Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28630338 | 0.86 | ALDH1A1 (0.52) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL14828743 | 0.83 | ALDH1A1 (0.53) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL6217005 | 0.82 | ALDH1A1 (0.48) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL7477617 | 0.80 | ALDH1A1 (0.47) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL14664143 | 0.79 | MAPT (0.50) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL687742 | 0.79 | ALDH1A1 (0.49) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 | |
| Acetic Acid SCHEMBL30330510 | 0.78 | RAB9A (0.49) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11366434 | 0.77 | PTGS1 (0.44) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL2828704 | 0.77 | RECQL (0.55) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 | |
| SCHEMBL11438082 | 0.77 | PCSK9 (0.51) | ALDH1A1RECQLCYP1A2CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106479334-A | A kind of Graphene heavy antisepsis environmental protection hard repair paint and preparation method thereof | 中兴通讯股份有限公司 | 2017-03-08 | — | — | CN | claimed |
| WO-2009072139-A1 | PROCESS FOR PRODUCING 2-[1-METHYL-5-(4-METHYLBENZOYL)- PYRROL-2- YL]ACETIC ACID OR SALT THEREOF | MATRIX LABORATORIES LIMITED (IN) | 2009-06-11 | — | — | WO | claimed |
| EP-0023938-B1 | PREPARATION OF PYRROLE-2-ACETATES | McNeilab, Inc. (US) | 1983-07-20 | — | — | EP | claimed |
| EP-0010553-B1 | PROCESS OF REDUCING A LOWERALKYL 1-LOWERALKYL-PYRROLE-2-GLYOXYLATE TO A LOWERALKYL 1-LOWERALKYL-PYRROLE-2-ACETATE | McNeilab, Inc. (US) | 1983-05-18 | — | — | EP | claimed |
| US-4284562-A | Process for preparing pyrrole-2-acetic acids | MCNEILAB, INC. (US) | 1981-08-18 | — | — | US | claimed |
| EP-0023938-A1 | Preparation of pyrrole-2-acetates | McNeilab, Inc. (US) | 1981-02-18 | — | — | EP | claimed |
| US-4216150-A | Preparation of pyrrole-2-acetates | MCNEIL LAB, INC. (US) | 1980-08-05 | — | — | US | claimed |
| US-4207237-A | Preparation of pyrrole-2-acetates | MCNEILAB, INC. (US) | 1980-06-10 | — | — | US | claimed |
| JP-54041869-A | — | — | None | — | — | JP | disclosed |
| JP-61227563-A | — | — | None | — | — | JP | disclosed |
| JP-57183758-A | — | — | None | — | — | JP | disclosed |
| EP-4630406-A1 | AMIDE COMPOUNDS AS ACTIVATORS OF THE POTASSIUM CHANNELS KV7.2/KV7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS | ANGELINI PHARMA S.P.A. (IT) | 2025-10-15 | — | — | EP | disclosed |
| US-20240417379-A1 | P2X4 RECEPTOR ANTAGONIST | NIPPON CHEMIPHAR CO., LTD (JP) | 2024-12-19 | — | — | US | disclosed |
| US-12116351-B2 | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO., LTD (JP) | 2024-10-15 | — | — | US | disclosed |
| US-4125537-A | REDUCTION OF PYRROLE-2-GLYOXYLATES AMINE CATALYZED ACTION OF HYDROGEN SULFIDE IN TERTIARY AMINE SOLVENT | MCNEIL LABORATORIES, INCORPORATED (US) | 1978-11-14 | — | — | US | disclosed |
| US-4115385-A | PENICILLINS | PFIZER INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-3998844-A | WITH AN AROYL CHLORIDE TO FORM A 5-AROYL-1-ALKYLPYRROLE-2-ACETIC ACID DERIVATIVE | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-12-27 | — | — | US | disclosed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | disclosed |
| US-3957818-A | PREPARATION OF PYRROLE-2-ACETIC ACID DERIVATIVES | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-05-18 | — | — | US | disclosed |
| US-3952012-A | MULTISTAGE | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240417379-A1 | P2X4 RECEPTOR ANTAGONIST | P2RX7, P2RX1, P2RX2 | ALDH1A1 3045/4885RECQL 713/4885CYP1A2 1195/4885 |
| US-12116351-B2 | P2X4 receptor antagonist | P2RX7, P2RX1, P2RX2 | ALDH1A1 3019/4885RECQL 1166/4885CYP1A2 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.