Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.46 |
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207386 | 0.88 | MEN1 (0.52) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL11047126 | 0.81 | TDP1 (0.56) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL8360771 | 0.76 | MEN1 (0.39) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL10482222 | 0.73 | TLR8 (0.60) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL8360769 | 0.72 | TSHR (0.41) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL4363285 | 0.71 | MEN1 (0.59) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL11283981 | 0.71 | TDP1 (0.51) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL27474614 | 0.70 | PDE7A (0.66) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL7169064 | 0.70 | TDP1 (0.40) | MEN1KMT2ATDP1TTRALB | |
| SCHEMBL997994 | 0.70 | CASP1 (0.48) | KMT2ATDP1MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58124758-A | — | — | None | — | — | JP | disclosed |
| JP-S58124758-A | BENZENESULFONAMIDE DERIVATIVE | FUJISAWA PHARMACEUT CO LTD | 1983-07-25 | — | — | JP | disclosed |