Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5682816 | 0.89 | CASP1 (0.52) | CASP1LMNAGAAKMT2APTGS2 | |
| SCHEMBL7205989 | 0.87 | TRPV4 (0.42) | CASP1LMNAGAAPGRMAPT | |
| SCHEMBL31387938 | 0.87 | TRPV4 (0.42) | CASP1LMNAGAAPGRMAPT | |
| SCHEMBL7386055 | 0.87 | TRPV4 (0.46) | LMNAKMT2APGRMAPTALDH1A1 | |
| SCHEMBL30307015 | 0.87 | TRPV4 (0.46) | LMNAKMT2APGRMAPTALDH1A1 | |
| SCHEMBL926865 | 0.87 | CA12 (0.49) | CASP1LMNAMAPTALDH1A1TDP1 | |
| SCHEMBL7427039 | 0.85 | CA12 (0.44) | CASP1PTGS2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL6249693 | 0.85 | CASP1 (0.51) | CASP1LMNAALDH1A1TDP1CA1 | |
| SCHEMBL6053382 | 0.85 | POLB (0.41) | CASP1LMNAGAAKMT2APTGS2 | |
| SCHEMBL146565 | 0.83 | CASP1 (0.50) | CASP1LMNAGAAKMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457140-A2 | Phenoxyphenyl sulfonyl compounds | BAYER AG (DE) | 1991-11-21 | — | — | EP | claimed |
| EP-0362606-A1 | Substituted phenoxyphenyl sulfonyl azoles, process for their preparation and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1990-04-11 | — | — | EP | claimed |
| JP-57085364-A | — | — | None | — | — | JP | disclosed |
| JP-11060551-A | — | — | None | — | — | JP | disclosed |
| JP-4226955-A | — | — | None | — | — | JP | disclosed |
| US-8513424-B2 | Pyridone GPR119 G protein-coupled receptor agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-08-20 | — | — | US | disclosed |
| US-20120258959-A1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2012-10-11 | — | — | US | disclosed |
| US-8232404-B2 | Pyridone GPR119 G protein-coupled receptor agonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-07-31 | — | — | US | disclosed |
| EP-2456435-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | The Board of Trustees of The Leland Stanford Junior University (US) | 2012-05-30 | — | — | EP | disclosed |
| EP-2393495-A1 | CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2011-12-14 | — | — | EP | disclosed |
| US-20110245227-A1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2011-10-06 | — | — | US | disclosed |
| EP-0569193-A1 | N-isoxazole-phenylsulfonamide derivatives and their use as endothelin antagonists | E.R. SQUIBB & SONS, INC. (US) | 1993-11-10 | — | — | EP | disclosed |
| JP-H04226955-A | PHENOXY PHENYL SULFONYL COMPOUND | BAYER AG | 1992-08-17 | — | — | JP | disclosed |
| EP-0457140-A2 | Phenoxyphenyl sulfonyl compounds | BAYER AG (DE) | 1991-11-21 | — | — | EP | disclosed |
| US-4969948-A | Herbicidal and plant growth-regulating substituted phenoxyphenylsulphonylazoles, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-13 | — | — | US | disclosed |
| EP-0362606-A1 | Substituted phenoxyphenyl sulfonyl azoles, process for their preparation and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1990-04-11 | — | — | EP | disclosed |
| EP-0259754-A2 | Flexible circuits | BAYER AG (DE) | 1988-03-16 | — | — | EP | disclosed |
| JP-S5785364-A | DIPHENYL SULFONE DERIVATIVE, ITS PREPARATION AND HERBICIDE CONTAINING THE SAME AS ACTIVE CONSTITUENT | SUMITOMO CHEM CO LTD | 1982-05-28 | — | — | JP | disclosed |
| EP-0000359-B1 | PHENOXY-PHENYLSULFINYL-AND-SULFONYLALKANECARBOXYLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS. | CIBA-GEIGY AG (CH) | 1981-10-21 | — | — | EP | disclosed |
| EP-0000359-A1 | Phenoxy-phenylsulfinyl-and-sulfonylalkanecarboxylic acid derivatives, method for their preparation and their use as herbicides and plant growth regulators. | CIBA-GEIGY AG (CH) | 1979-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120258959-A1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | GPR119, GPR65, GPR27 | CASP1 2893/4885LMNA 3603/4885GAA 3013/4885 |
| US-20110245227-A1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | GPR119, GPR65, GPR27 | CASP1 2893/4885LMNA 3603/4885GAA 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.