Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988786 | 0.72 | KDM4E (0.55) | KDM4ELMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL30200165 | 0.72 | KDM4E (0.55) | KDM4ELMNAMAPTALDH1A1HSD17B10 | |
| SCHEMBL5959482 | 0.69 | PGR (0.52) | KDM4EMAPK1LMNAMAPTPARP1 | |
| SCHEMBL6556019 | 0.68 | PARP1 (0.50) | KDM4ELMNAMAPTPARP1ALDH1A1 | |
| SCHEMBL21588776 | 0.67 | KDM4E (0.40) | KDM4EMAPK1MAPTPARP1ALDH1A1 | |
| SCHEMBL29814593 | 0.67 | KDM4E (0.40) | KDM4EMAPK1MAPTPARP1ALDH1A1 | |
| SCHEMBL11541130 | 0.67 | CYP2A6 (0.49) | KDM4EMAPK1LMNAMAPTPARP1 | |
| SCHEMBL10524288 | 0.67 | KDM4E (0.50) | KDM4EMAPK1LMNAMAPTALDH1A1 | |
| SCHEMBL6266662 | 0.67 | CA2 (0.61) | KDM4ELMNAMAPTTHRBALDH1A1 | |
| SCHEMBL9205461 | 0.67 | MAPK1 (0.41) | KDM4EMAPK1LMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094769-A1 | Preparing 7-alkoxybenzofurans and intermediates used therein | THE UPJOHN COMPANY (US) | 1983-11-23 | — | — | EP | claimed |