SCHEMBL5959482

SCHEMBL5959482

CC(=O)Oc1cccc2c1C(=O)OCC2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.52
HTR2A P28223 2/20 0.41
DRD2 P14416 1/20 0.41
KDM4E B2RXH2 4/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPK1 P28482 2/20 0.41
TTR P02766 2/20 0.41
HPGD P15428 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
ADORA2A P29274 2/20 0.41
ADORA1 P30542 2/20 0.41
MEN1 O00255 1/20 0.41
ABCC4 O15439 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
HSP90AA1 P07900 1/20 0.41
CHRM2 P08172 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11735130 0.78 PGR (0.43) PGRHTR2ADRD2KDM4EALDH1A1
SCHEMBL1645515 0.76 ALDH1A1 (0.50) PGRHTR2ADRD2KDM4EALDH1A1
SCHEMBL13925640 0.74 MAOA (0.63) HTR2ADRD2KDM4EALDH1A1MAPK1
SCHEMBL13021607 0.73 MAOA (0.49) HTR2ADRD2KDM4EALDH1A1HPGD
SCHEMBL9959163 0.73 MAOA (0.53) KDM4EALDH1A1MAPK1HPGDMAPT
SCHEMBL11271210 0.73 ALDH1A1 (0.54) PGRHTR2ADRD2KDM4EALDH1A1
SCHEMBL11486604 0.73 DRD2 (0.44) DRD2KDM4EALDH1A1MAPTKMT2A
SCHEMBL2808611 0.72 PARP1 (0.51) KDM4EALDH1A1MAPTLMNAHTT
SCHEMBL5951589 0.72 ABCB1 (0.50) HTR2ADRD2KDM4EALDH1A1MAPK1
SCHEMBL343377 0.72 ALDH1A1 (0.60) HTR2AKDM4EALDH1A1MAPK1TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9829433-B2 Imaging techniques and associated apparatus TERAVIEW LIMITED (GB) 2017-11-28 US disclosed
US-20060235621-A1 Imaging techniques and associated apparatus ETV CAPITAL S.A. (LU) 2006-10-19 US disclosed
EP-1581799-A1 IMAGING TECHNIQUES AND ASSOCIATED APPARATUS Teraview Limited (GB) 2005-10-05 EP disclosed
WO-2004063726-A1 IMAGING TECHNIQUES AND ASSOCIATED APPARATUS TERAVIEW LIMITED (GB) 2004-07-29 WO disclosed
US-5238686-A Microcapsules of dual walled coated medicament KINAFORM TECHNOLOGY, INC. (US) 1993-08-24 US disclosed
EP-0239361-B1 SUSTAINED-RELEASE PHARMACEUTICAL PREPARATION KINAFORM TECHNOLOGY, INC. (US) 1992-12-02 EP disclosed
EP-0239361-A1 Sustained-release pharmaceutical preparation KINAFORM TECHNOLOGY, INC. (US) 1987-09-30 EP disclosed