Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11205507 | 0.96 | NAAA (0.42) | KDM4EGAASTAT1RAB9ACYP4F2 | |
| SCHEMBL11205681 | 0.86 | MAPT (0.42) | KDM4ERAB9ACYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL11204391 | 0.86 | MAPT (0.36) | KDM4EMEN1KMT2ALMNANAAA | |
| SCHEMBL11203221 | 0.86 | THRB (0.43) | KDM4ECYP4F2CYP4A11L3MBTL1MEN1 | |
| SCHEMBL11207157 | 0.86 | KMT2A (0.45) | L3MBTL1MEN1KMT2ALMNAPOLB | |
| SCHEMBL11205182 | 0.85 | NAAA (0.42) | KDM4EGAASTAT1RAB9ACYP4F2 | |
| SCHEMBL7422714 | 0.83 | MEN1 (0.43) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11202086 | 0.83 | CYP4F2 (0.42) | CYP4F2CYP4A11MAOBPPARGPPARA | |
| SCHEMBL11207422 | 0.82 | KCNA3 (0.42) | MEN1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL11201942 | 0.81 | THRA (0.36) | KDM4EMEN1KMT2ALMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |