Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432809 | 0.95 | LMNA (0.41) | LMNAPOLBPKMMAPTALDH1A1 | |
| SCHEMBL7431043 | 0.94 | ALDH1A1 (0.41) | LMNAPOLBPKMMAPTALDH1A1 | |
| SCHEMBL11017511 | 0.92 | ALDH1A1 (0.41) | LMNAPOLBPKMMAPTALDH1A1 | |
| SCHEMBL11207157 | 0.92 | KMT2A (0.45) | LMNAPOLBPKMMAPTALDH1A1 | |
| SCHEMBL7485729 | 0.91 | LMNA (0.39) | LMNAPOLBPKMMAPTALDH1A1 | |
| SCHEMBL11207422 | 0.90 | KCNA3 (0.42) | LMNAPOLBPKMMAPTALDH1A1 | |
| SCHEMBL7428632 | 0.89 | NAAA (0.39) | LMNAPOLBPKMMAPTALDH1A1 | |
| SCHEMBL11201202 | 0.89 | KCNA3 (0.41) | LMNAPOLBPKMMAPTALDH1A1 | |
| SCHEMBL11203299 | 0.89 | KCNA3 (0.41) | LMNAPOLBPKMMAPTALDH1A1 | |
| SCHEMBL11206024 | 0.89 | KCNA3 (0.41) | LMNAPOLBPKMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046590-B1 | PHEN(ALK)OXY-SUBSTITUTED OXIRANE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND DRUGS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1985-05-22 | — | — | EP | disclosed |