Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207898 | 0.86 | KDM4E (0.42) | SMN1; SMN2GAAKDM4EALDH1A1LMNA | |
| SCHEMBL11202760 | 0.72 | KCNA5 (0.42) | SMN1; SMN2GAAKDM4EALDH1A1LMNA | |
| SCHEMBL31560783 | 0.71 | GLA (0.43) | SMN1; SMN2GAAKDM4EALDH1A1LMNA | |
| SCHEMBL6995111 | 0.70 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAMEN1KMT2AKDM4E | |
| SCHEMBL24051897 | 0.69 | MTNR1A (0.49) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6239887 | 0.66 | CYP4F2 (0.59) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7606587 | 0.65 | HSP90AA1 (0.54) | GAAKDM4EALDH1A1LMNAMTNR1A | |
| SCHEMBL13607458 | 0.65 | HSP90AA1 (0.54) | SMN1; SMN2KDM4EALDH1A1LMNANPC1 | |
| SCHEMBL24303072 | 0.65 | SMN1; SMN2 (0.39) | SMN1; SMN2GAAKDM4EALDH1A1LMNA | |
| SCHEMBL1870609 | 0.65 | ALDH1A1 (0.62) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094833-A2 | Novel 1,2-benzisoxazole derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1983-11-23 | — | — | EP | disclosed |