Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27803914 | 0.85 | MAPT (0.48) | HSP90AA1PKML3MBTL1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL28880679 | 0.83 | KDM4E (0.54) | HSP90AA1KDM4ETSHRPOLBMAPT | |
| SCHEMBL18481212 | 0.81 | MAPT (0.42) | PKML3MBTL1KDM4EALDH1A1APOBEC3G | |
| SCHEMBL24051897 | 0.81 | MTNR1A (0.49) | HSP90AA1L3MBTL1KDM4EALDH1A1RAB9A | |
| SCHEMBL971350 | 0.80 | L3MBTL1 (0.50) | HSP90AA1PKML3MBTL1KDM4EALDH1A1 | |
| SCHEMBL28023498 | 0.79 | HSP90AA1 (0.46) | HSP90AA1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4126633 | 0.78 | P2RX7 (0.45) | HSP90AA1PKMKDM4EALDH1A1RAB9A | |
| SCHEMBL18512291 | 0.78 | SLC13A5 (0.50) | PKML3MBTL1KDM4ERAB9ALMNA | |
| SCHEMBL4500023 | 0.78 | L3MBTL1 (0.60) | HSP90AA1PKML3MBTL1KDM4EALDH1A1 | |
| SCHEMBL3946071 | 0.77 | PPIA (0.52) | LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298835-A1 | NOVEL SCAFFOLDS FOR ALPHA-HELIX MIMICRY | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-12-03 | — | — | US | disclosed |
| US-7579350-B2 | 5-Isobutyl-6-4-isopropyl-4,5-dihydro-oxazol-2-yl)-pyridazin-3-yl]-piperidin-1-yl-methanone; mimetics of functionalized pyridazine derivatives having low molecular weight; alpha-helical binding ligands of natural receptors such as those of the peptide galanin or the protein Bcl | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298835-A1 | NOVEL SCAFFOLDS FOR ALPHA-HELIX MIMICRY | HRH1, HEATR1, PLEKHA1 | HSP90AA1 665/4885PKM 3383/4885L3MBTL1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.