Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E388 SCHEMBL11200228 | 0.89 | LMNA (0.47) | LMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL11170124 | 0.83 | BHMT (0.42) | LMNAKMT2AHSD17B10TDP1 | |
| SCHEMBL11202584 | 0.81 | TSHR (0.45) | LMNAKMT2AHSD17B10TDP1 | |
| Malonic Acid SCHEMBL11497552 | 0.78 | LDHA (0.33) | LMNA | |
| SCHEMBL3062802 | 0.76 | LMNA (0.34) | LMNA | |
| SCHEMBL8905904 | 0.75 | LIMK1 (0.36) | LMNA | |
| Adipic Acid SCHEMBL11497568 | 0.75 | LMNA (0.41) | LMNAKMT2AHSD17B10TDP1 | |
| Malonic Acid SCHEMBL11132579 | 0.75 | LDHA (0.36) | — | |
| SCHEMBL11202657 | 0.74 | BHMT (0.38) | HSD17B10 | |
| SCHEMBL11194793 | 0.72 | GMNN (0.42) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4367216-A | X-RAYS, CONTRAST, OPACITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-01-04 | — | — | US | disclosed |