Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL11497552 | 0.90 | LDHA (0.33) | LMNA | |
| SCHEMBL8905904 | 0.90 | LIMK1 (0.36) | LMNA | |
| SCHEMBL9843247 | 0.80 | — | — | |
| SCHEMBL9843372 | 0.80 | — | — | |
| SCHEMBL9787607 | 0.80 | ALDH1A1 (0.39) | — | |
| SCHEMBL9009368 | 0.79 | LMNA (0.43) | LMNA | |
| SCHEMBL5301790 | 0.78 | LMNA (0.58) | LMNA | |
| SCHEMBL11708490 | 0.78 | TSHR (0.41) | LMNA | |
| Hydrochloric Acid SCHEMBL4589564 | 0.77 | LMNA (0.42) | LMNA | |
| SCHEMBL10714137 | 0.77 | LIMK1 (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742926-A1 | MACROCYCLE-SUBSTITUTED TRIMER HALOGEN-BENZOL DERIVATIVES | Schering Aktiengesellschaft (DE) | 2007-01-17 | — | — | EP | claimed |
| WO-2005108379-A1 | MACROCYCLE-SUBSTITUTED TRIMER HALOGEN-BENZOL DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-11-17 | — | — | WO | claimed |
| CN-104356023-A | Preparation method of iotrolan | WUHAN INST TECHNOLOGY | 2015-02-18 | — | — | CN | disclosed |
| EP-2200656-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-12-05 | — | — | EP | disclosed |
| EP-2200656-B1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2012-12-05 | — | — | EP | disclosed |
| US-8323619-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-12-04 | — | — | US | disclosed |
| US-8323619-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-12-04 | — | — | US | disclosed |
| US-8323619-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-12-04 | — | — | US | disclosed |
| US-8202511-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-06-19 | — | — | US | disclosed |
| US-8202511-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-06-19 | — | — | US | disclosed |
| US-8202511-B2 | Contrast agents | GE HEALTHCARE AS (NO) | 2012-06-19 | — | — | US | disclosed |
| EP-0317492-A2 | Substituted dicarboxylic acids-bis(3,5-dicarbamoyl-2,4,6-triiodo-anilides), process for their preparation and X-ray contrast agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-05-24 | — | — | EP | disclosed |
| EP-0308364-A2 | Dicarboxylic acid-bis(3,5-dicarbamoyl-2-4-6-triiodanilides), process for their preparation and X-ray contrast agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | disclosed |
| EP-0160036-A4 | NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA. | BIOPHYSICA FOUNDATION (US) | 1987-06-11 | — | — | EP | disclosed |
| EP-0160036-A1 | NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA | BIOPHYSICA FOUNDATION (US) | 1985-11-06 | — | — | EP | disclosed |
| WO-1985001727-A1 | NOVEL SYNTHETIC METHODS FOR NON-IONIC RADIOGRAPHIC CONTRAST MEDIA | BIOPHYSICA FOUNDATION (US) | 1985-04-25 | — | — | WO | disclosed |
| US-4367216-A | X-RAYS, CONTRAST, OPACITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-01-04 | — | — | US | disclosed |
| US-4364921-A | RADIOPACITY | SCHERING, AKTIENGESELLSCHAFT (DE) | 1982-12-21 | — | — | US | disclosed |
| US-4352788-A | ARTERIES | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1982-10-05 | — | — | US | disclosed |
| US-4239747-A | Dicarboxylic acid bis(3,5-dicarbamoyl-2,4,6-triiodoanilides) useful as x-ray contrast agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | disclosed |