SCHEMBL11207293

SCHEMBL11207293

OC(Oc1c(Br)cc(Br)cc1Br)C(Br)CBr

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX15 P16050 3/20 0.32
ALOX12 P18054 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11207294 0.72 TSHR (0.33) TSHRHSD17B10CYP3A4TDP1ALOX15
SCHEMBL6285002 0.70 HSD17B10 (0.41) TSHRHSD17B10CYP3A4TDP1ALOX15
SCHEMBL681064 0.69 HSD17B10 (0.38) TSHRHSD17B10CYP3A4TDP1ALOX15
SCHEMBL2883398 0.66 ALDH1A1 (0.44) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL10192340 0.66 ALDH1A1 (0.44) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL9816242 0.65 CYP3A4 (0.30) TSHRCYP3A4TDP1
SCHEMBL5440832 0.65 ALDH1A1 (0.67) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL22892551 0.65 TSHR (0.34) TSHRHSD17B10CYP3A4TDP1ALOX15
SCHEMBL1537774 0.65 HSD17B10 (0.39) TSHRALDH1A1HSD17B10CYP3A4TDP1
SCHEMBL765589 0.65 ALOX12 (0.47) TSHRALDH1A1HSD17B10CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026310-B1 FIRE PROTECTION FINISH FOR RESOL-TYPE RESINOUS LAMINATES Chemische Fabrik Kalk GmbH (DE) 1983-07-27 EP disclosed