Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.70 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | CRHBP | P24387 | 2/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29513025 | 0.93 | KMT2A (0.76) | KMT2APKMPRSS1KDM4ELMNA | |
| SCHEMBL29513074 | 0.90 | PRSS1 (0.75) | KMT2APKMPRSS1KDM4ELMNA | |
| SCHEMBL29513080 | 0.90 | PRSS1 (0.77) | KMT2APKMPRSS1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL28720505 | 0.87 | KMT2A (0.69) | KMT2APKMPRSS1KDM4ELMNA | |
| SCHEMBL22118764 | 0.87 | HCAR3 (0.78) | KMT2APKMPRSS1KDM4ELMNA | |
| SCHEMBL1066375 | 0.87 | HCAR3 (0.77) | KMT2APKMMAPTHCAR3ALDH1A1 | |
| SCHEMBL22121008 | 0.86 | KMT2A (0.67) | KMT2APKMPRSS1KDM4ELMNA | |
| SCHEMBL19451789 | 0.85 | PRSS1 (0.68) | KMT2APKMPRSS1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL28722113 | 0.85 | PRSS1 (0.68) | KMT2APKMPRSS1KDM4ELMNA | |
| SCHEMBL5674224 | 0.84 | HCAR3 (0.76) | KMT2APKMPRSS1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 776 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799092-B2 | Composition for simultaneously bleaching and dyeing keratin fibers, comprising at least one anionic or nonionic direct dye and at least one associative polymer | L'OREAL S.A. (FR) | 2010-09-21 | — | — | US | claimed |
| US-7736395-B2 | direct dyes | L'OREAL S.A. (FR) | 2010-06-15 | — | — | US | claimed |
| EP-1738800-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1738801-B1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| US-20070033743-A1 | direct dyes | L'OREAL S.A. (FR) | 2007-02-15 | — | — | US | claimed |
| CN-1903161-A | Composition for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | OREAL (FR) | 2007-01-31 | — | — | CN | claimed |
| CN-1899244-A | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | OREAL (FR) | 2007-01-24 | — | — | CN | claimed |
| EP-1738800-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-1738801-A1 | Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| EP-0646109-B1 | NOVEL HYDROXYETHYLATED 2-NITRO-P-PHENYLENEDIAMINES AND USE THEREOF FOR DYEING KERATIN FIBRES | OREAL (FR) | 1997-09-03 | — | — | EP | claimed |
| EP-0673926-B1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | OREAL (FR) | 1997-04-09 | — | — | EP | claimed |
| EP-0487205-B1 | Compositions containing nitroaniline dyes having a carbamide substituent group | BRISTOL MYERS SQUIBB CO (US) | 1996-08-21 | — | — | EP | claimed |
| US-5516942-A | DIRECT DYES FOR HAIR FOR YELLOW OR PURPLE | L'OREAL (FR) | 1996-05-14 | — | — | US | claimed |
| EP-0673926-A1 | 2-Nitro-p-phenylenediamines having a sulfur atom in position 5, process for their preparation, dye compositions containing them and their use for dyeing keratinic fibres | L'OREAL (FR) | 1995-09-27 | — | — | EP | claimed |
| EP-0646108-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1995-04-05 | — | — | EP | claimed |
| WO-1994000414-A1 | HYDROXYPROPYLATED 2-NITRO-P-PHENYLENEDIAMINES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR DYEING KERATIN FIBRES | L'OREAL (FR) | 1994-01-06 | — | — | WO | claimed |
| US-5171889-A | Yellow hair dyes | CLAIROL INCORPORATED (US) | 1992-12-15 | — | — | US | claimed |
| EP-0487205-A2 | Compositions containing nitroaniline dyes having a carbamide substituent group | Bristol-Myers Squibb Company (US) | 1992-05-27 | — | — | EP | claimed |
| US-5042988-A | Compositions containing nitroaniline dyes having a carbamide substituent group | CLAIROL INCORPORATED (US) | 1991-08-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033744-A1 | Anhydrous composition; nonionic or anionic direct dye, associative polymer, peroxygenated salt, and alkaline agent; hair dyes suitable for dark hair; easy to use and can produce chromatic and fast coloration | KRT18, BRD7, KAT7 | KMT2A 254/4885PKM 1394/4885PRSS1 3483/4885 |
| US-20070033743-A1 | direct dyes | KRT18, DSG1, DSP | KMT2A 243/4885PKM 1116/4885PRSS1 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.