Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.64 |
| ▸ | HTR2A | P28223 | 4/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683692 | 0.90 | L3MBTL1 (0.56) | HTR7HTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL10722927 | 0.85 | LMNA (0.58) | HTR7HTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL11156121 | 0.85 | HTR2A (0.66) | HTR7HTR2ASMN1; SMN2HTR1ACYP1A2 | |
| SCHEMBL11159815 | 0.83 | L3MBTL1 (0.70) | HTR7HTR2AHTR1ADRD2DRD3 | |
| SCHEMBL11152655 | 0.83 | HTR2A (0.59) | HTR7HTR2ASMN1; SMN2DRD2DRD3 | |
| SCHEMBL2296651 | 0.79 | L3MBTL1 (0.73) | HTR7HTR2AHTR1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL2297385 | 0.78 | L3MBTL1 (0.72) | HTR7HTR2AHTR1ADRD2DRD3 | |
| SCHEMBL682820 | 0.77 | L3MBTL1 (0.73) | HTR7HTR2AHTR1ADRD2DRD3 | |
| SCHEMBL684065 | 0.77 | HTR2A (0.52) | HTR7HTR2ASMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL683646 | 0.77 | HTR2A (0.52) | HTR2ASMN1; SMN2CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58148820-A | — | — | None | — | — | JP | disclosed |
| JP-S58148820-A | AMELIORANT FOR CEREBRAL CIRCULATORY METABOLISM CONTAINING THEOBROMINE DERIVATIVE AS ACTIVE CONSTITUENT | EISAI CO LTD | 1983-09-05 | — | — | JP | disclosed |