SCHEMBL682820

SCHEMBL682820

COc1ccccc1N1CCN(Cn2cnc3c2c(=O)n(C)c(=O)n3C)CC1

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.73
HTR7 P34969 2/20 0.59
HTR1A P08908 6/20 0.56
HTR2A P28223 4/20 0.56
HTR6 P50406 1/20 0.55
ALOX15 P16050 1/20 0.55
DRD2 P14416 1/20 0.54
DRD3 P35462 1/20 0.54
TSHR P16473 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2296651 0.92 L3MBTL1 (0.73) L3MBTL1HTR7HTR1AHTR2AHTR6
Hydrochloric Acid SCHEMBL2297385 0.91 L3MBTL1 (0.72) L3MBTL1HTR7HTR1AHTR2AHTR6
SCHEMBL11159815 0.90 L3MBTL1 (0.70) L3MBTL1HTR7HTR1AHTR2AHTR6
SCHEMBL682810 0.86 HTR7 (0.58) L3MBTL1HTR7HTR6TSHR
SCHEMBL684356 0.86 HTR7 (0.58) L3MBTL1HTR7HTR6TSHR
SCHEMBL683692 0.83 L3MBTL1 (0.56) L3MBTL1HTR7HTR1AHTR2A
SCHEMBL683655 0.83 HTR7 (0.77) L3MBTL1HTR7HTR1AHTR2AHTR6
SCHEMBL682816 0.82 TSHR (0.55) L3MBTL1HTR7HTR6TSHR
SCHEMBL683604 0.81 RXFP1 (0.62) L3MBTL1HTR7HTR6ALOX15TSHR
SCHEMBL683994 0.81 RXFP1 (0.63) L3MBTL1HTR7HTR1AHTR2AHTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110269717-A1 NEUROGENESIS BY MODULATING ANGIOTENSIN BRAINCELLS INC. (US) 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269717-A1 NEUROGENESIS BY MODULATING ANGIOTENSIN NGF, DCX, BDNF L3MBTL1 4624/4885HTR7 1398/4885HTR1A 1265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.