SCHEMBL683692

SCHEMBL683692

COc1ccccc1N1CCN(Cn2c(=O)c3c(ncn3C)n(C)c2=O)CC1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.56
ALDH1A1 P00352 1/20 0.55
ADRA2A P08913 1/20 0.55
MAPT P10636 1/20 0.55
ADRA2B P18089 1/20 0.55
ADRA2C P18825 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
HTR7 P34969 1/20 0.54
ADORA2B P29275 1/20 0.51
HTR2A P28223 5/20 0.50
HTR1A P08908 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11207435 0.90 HTR7 (0.64) L3MBTL1ALDH1A1ADRA2AMAPTADRA2B
SCHEMBL684065 0.87 HTR2A (0.52) SMN1; SMN2HTR7ADORA2BHTR2A
SCHEMBL683646 0.87 HTR2A (0.52) SMN1; SMN2ADORA2BHTR2A
SCHEMBL684023 0.83 HTR2A (0.58) L3MBTL1ALDH1A1SMN1; SMN2HTR7ADORA2B
SCHEMBL682820 0.83 L3MBTL1 (0.73) L3MBTL1HTR7HTR2AHTR1A
SCHEMBL683696 0.83 HTR2A (0.48) ALDH1A1SMN1; SMN2ADORA2BHTR2A
SCHEMBL684375 0.82 ADORA2B (0.53) ALDH1A1MAPTSMN1; SMN2ADORA2BHTR2A
SCHEMBL684068 0.81 ADORA2B (0.50) ADRA2AADRA2CHTR7ADORA2BHTR2A
SCHEMBL684062 0.81 HTR2A (0.52) ALDH1A1SMN1; SMN2ADORA2BHTR2A
SCHEMBL683640 0.79 HTR2A (0.51) SMN1; SMN2ADORA2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110269717-A1 NEUROGENESIS BY MODULATING ANGIOTENSIN BRAINCELLS INC. (US) 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269717-A1 NEUROGENESIS BY MODULATING ANGIOTENSIN NGF, DCX, BDNF L3MBTL1 4624/4885ALDH1A1 1565/4885ADRA2A 584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.