Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057154 | 1.00 | LMNA (0.42) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL7056921 | 1.00 | LMNA (0.42) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL4766710 | 1.00 | LMNA (0.42) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL3796584 | 1.00 | LMNA (0.42) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL6057209 | 1.00 | LMNA (0.42) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL11210376 | 0.97 | DNM1 (0.46) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL3481447 | 0.97 | DNM1 (0.46) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL27323251 | 0.97 | DNM1 (0.46) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL4770413 | 0.97 | OPRM1 (0.42) | LMNATSHRTHRBDNM1OPRM1 | |
| SCHEMBL2772318 | 0.95 | LMNA (0.39) | LMNATSHRTHRBDNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017734-B1 | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING CARBON BLACK, METHOD FOR PREPARING THE SAME AND METHOD FOR CURING THE COMPOSITIONS | SWS Silicones Corporation (US) | 1983-04-13 | — | — | EP | disclosed |
| EP-0017734-A1 | Curable organopolysiloxane compositions containing carbon black, method for preparing the same and method for curing the compositions | SWS Silicones Corporation (US) | 1980-10-29 | — | — | EP | disclosed |
| US-4221693-A | ROOM TEMPERATURE VULCANIZED SILICONE RUBBERS | WACKER SILICONES CORPORATION | 1980-09-09 | — | — | US | disclosed |
| US-4111890-A | CURABLE ORGANOPOLYSILOXANE COMPOSITIONS CONTAINING TITANIUM ESTERS | SWS SILICONES CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |