Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | F12 | P00748 | 1/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | SI | P14410 | 1/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554573 | 0.82 | ALOX15 (0.54) | KMT2ACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL11206432 | 0.82 | KMT2A (0.59) | KMT2ACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL1685055 | 0.80 | HSD17B10 (0.61) | KMT2ACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL16147361 | 0.76 | ALDH1A1 (0.74) | KMT2AGAAALDH1A1HTTNPC1 | |
| SCHEMBL6954737 | 0.75 | ALOX15 (0.58) | KMT2ACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL16147363 | 0.74 | FGFR1 (0.62) | KMT2ACYP1A2CYP3A4CYP2C19GAA | |
| SCHEMBL204727 | 0.74 | ALOX15 (0.64) | KMT2ACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL11650354 | 0.72 | CA12 (0.58) | KMT2ACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL707209 | 0.72 | ALOX15 (0.58) | KMT2ACYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL18991593 | 0.72 | HSD17B10 (0.66) | CYP1A2CYP3A4CYP2C19CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023889-B1 | IMINOISOINDOLINONE METAL COMPLEXES, PROCESS FOR THEIR MANUFACTURE, METHOD FOR PIGMENTING AN ORGANIC HIGH-MOLECULAR MATERIAL AND HIGH-MOLECULAR ORGANIC MATERIAL CONTAINING SUCH A METAL COMPLEX | CIBA-GEIGY AG (CH) | 1983-03-09 | — | — | EP | disclosed |
| EP-0023889-A1 | Iminoisoindolinone metal complexes, process for their manufacture, method for pigmenting an organic high-molecular material and high-molecular organic material containing such a metal complex | CIBA-GEIGY AG (CH) | 1981-02-11 | — | — | EP | disclosed |