Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA3 | P07451 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA6 | P23280 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11206432 | 0.86 | KMT2A (0.59) | ALOX15HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL11207976 | 0.82 | KMT2A (0.62) | ALOX15HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL204727 | 0.80 | ALOX15 (0.64) | ALOX15HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL18797751 | 0.76 | L3MBTL1 (0.56) | KMT2ANPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL3563360 | 0.75 | KMT2A (0.80) | KMT2ANPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL11650354 | 0.75 | CA12 (0.58) | ALOX15HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL27644496 | 0.75 | MET (0.48) | ALOX15HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL6954737 | 0.75 | ALOX15 (0.58) | ALOX15HSD17B10KMT2ANPC1RAB9A | |
| SCHEMBL707209 | 0.75 | ALOX15 (0.58) | ALOX15HSD17B10KMT2ANPC1CA12 | |
| SCHEMBL1685055 | 0.74 | HSD17B10 (0.61) | ALOX15HSD17B10KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041470-A1 | METHODS AND COMPOSITIONS FOR SELECTIVE AND TARGETED CANCER THERAPY | Board Of Regents Of the University Of Texas System (US) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015035051-A1 | METHODS AND COMPOSITIONS FOR SELECTIVE AND TARGETED CANCER THERAPY | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-03-12 | — | — | WO | disclosed |