SCHEMBL11208014

SCHEMBL11208014

Cc1cc(Cc2ccccc2)c(O)c(C(C)c2cc(C)cc(Cc3ccccc3)c2O)c1

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.46
BCL2L1 Q07817 1/20 0.46
PTPN1 P18031 3/20 0.43
PTPN2 P17706 1/20 0.43
PTPN6 P29350 1/20 0.43
LDHA P00338 1/20 0.43
LDHB P07195 1/20 0.43
AMY1A P0DUB6 1/20 0.41
ALOX5 P09917 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11795618 0.90 LDHA (0.46) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL11206438 0.89 BCL2 (0.44) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL11245858 0.86 BCL2 (0.44) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL670158 0.84 BCL2 (0.57) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL225328 0.84 TYR (0.46) PTPN1PTPN2PTPN6AMY1A
SCHEMBL11568913 0.83 BCL2 (0.42) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL1904809 0.83 AMY1A (0.58) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL544660 0.80 BCL2 (0.52) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL8990148 0.80 BCL2 (0.52) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL21899356 0.77 TYR (0.46) AMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003338-B1 USE OF BENZYL-PHENOLS AS ANTIOXIDANTS BAYER AG (DE) 1983-03-09 EP disclosed
EP-0003338-A2 Use of benzyl-phenols as antioxidants BAYER AG (DE) 1979-08-08 EP disclosed