SCHEMBL8990148

SCHEMBL8990148

Cc1cc(Cc2ccccc2)c(O)c(-c2cc(C)cc(Cc3ccccc3)c2O)c1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.52
BCL2L1 Q07817 1/20 0.52
PTPN1 P18031 3/20 0.47
PTPN2 P17706 1/20 0.47
PTPN6 P29350 1/20 0.47
AMY1A P0DUB6 1/20 0.46
ALOX5 P09917 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL670158 0.90 BCL2 (0.57) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL1904809 0.89 AMY1A (0.58) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL11568910 0.85 LDHA (0.40) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL544660 0.85 BCL2 (0.52) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL14303046 0.82 BCL2 (0.48) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL1904779 0.81 BCL2 (0.47) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL9252181 0.80 PTPN1 (0.71) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL11208014 0.80 BCL2 (0.46) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL11795618 0.80 LDHA (0.46) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL4459522 0.80 HSPA5 (0.72) BCL2BCL2L1PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP claimed
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP disclosed
US-5262295-A Biphenyldihydroxide reducing agent for silver halide emulsion layers CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
EP-0509740-A1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KABUSHIKI KAISHA (JP) 1992-10-21 EP disclosed