Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208230 | 0.82 | MAPT (1.00) | MAPTALDH1A1TDP1TP53KMT2A | |
| SCHEMBL9427163 | 0.82 | MAPT (0.52) | MAPTALDH1A1TDP1TP53KMT2A | |
| SCHEMBL10744485 | 0.79 | PTGS2 (0.63) | KMT2AMEN1 | |
| SCHEMBL8975296 | 0.77 | BCHE (0.72) | ALDH1A1BCHEACHEKMT2AMEN1 | |
| SCHEMBL2836336 | 0.75 | BCHE (0.69) | BCHEACHEKMT2AMEN1POLB | |
| SCHEMBL15791835 | 0.73 | MAPT (0.70) | MAPTALDH1A1TDP1TP53KMT2A | |
| SCHEMBL11306682 | 0.73 | MAPT (0.70) | MAPTALDH1A1TDP1TP53KMT2A | |
| SCHEMBL11207452 | 0.73 | ALDH1A1 (1.00) | MAPTALDH1A1TDP1TP53KMT2A | |
| SCHEMBL21841445 | 0.73 | BCHE (0.51) | ALDH1A1BCHEACHEKMT2AMEN1 | |
| SCHEMBL11490893 | 0.73 | BCHE (0.51) | MAPTBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583151-A | PLANT SAFENING AGENTS, FUNGICIDES, MICROBIOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-10 | — | — | US | disclosed |