Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463126 | 0.82 | FFAR1 (0.55) | POLBGAAKDM4EMAPTHTT | |
| SCHEMBL11208287 | 0.81 | SMN1; SMN2 (0.56) | POLBGAAKDM4EMAPTHTT | |
| SCHEMBL10971632 | 0.78 | CA2 (0.47) | POLBGAAALDH1A1PKMMEN1 | |
| SCHEMBL9808053 | 0.78 | APP (0.43) | POLBGAAKDM4EMAPTHTT | |
| SCHEMBL11214234 | 0.76 | L3MBTL1 (0.48) | POLBMAPTALDH1A1PKMMEN1 | |
| SCHEMBL11214281 | 0.76 | APEX1 (0.46) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11218670 | 0.76 | DAO (0.43) | MAPTHTTALDH1A1KMT2AANPEP | |
| SCHEMBL6280628 | 0.75 | PTPN1 (0.54) | POLBGAAKDM4EMAPTALDH1A1 | |
| SCHEMBL9808202 | 0.75 | APP (0.41) | POLBGAAKDM4EMAPTHTT | |
| SCHEMBL9808177 | 0.73 | HTT (0.59) | POLBGAAKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |