Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 7/20 | 0.49 |
| ▸ | ALPL | P05186 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.49 |
| ▸ | ALPI | P09923 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | PLAA | Q9Y263 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281258 | 0.83 | MAPT (0.56) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL6280285 | 0.82 | MAPT (0.54) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL9376852 | 0.81 | ANPEP (0.61) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL9787355 | 0.81 | ALDH1A1 (0.59) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL9463126 | 0.80 | FFAR1 (0.55) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL19309449 | 0.80 | MEN1 (0.56) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL1355962 | 0.80 | CA1 (0.67) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL1447998 | 0.78 | APEX1 (0.75) | MEN1KMT2ANPC1ALDH1A1MAPT | |
| SCHEMBL28981219 | 0.77 | RAB9A (0.59) | PTPN1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL1447641 | 0.77 | CA1 (0.59) | MEN1KMT2ANPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921827-B2 | Process for preparing 3-aryl-benzo{b} thiophenes | ELI LILLY AND COMPANY (US) | 2005-07-26 | — | — | US | disclosed |
| US-20040132775-A1 | Process for preparing 3-aryl-benzo{b} thiophenes | LUKE WAYNE DOUGLAS (US) | 2004-07-08 | — | — | US | disclosed |
| WO-2002042261-A2 | PROCESS FOR PREPARING α-(3-ARYLTHIO)-ACETOPHENONES | ELI LILLY AND COMPANY (US) | 2002-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132775-A1 | Process for preparing 3-aryl-benzo{b} thiophenes | TBCB, CYP1B1, TST | PTPN1 3683/4885MEN1 1793/4885KMT2A 1939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.